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When we created Lutea, we didn't guess. We researched.
Every ingredient in our formula is backed by clinical studies specifically examining its effects on mood, stress response, hormone sensitivity, and the neurochemical pathways that PMDD disrupts.
These aren't random "women's health" ingredients. Each one targets specific systems that crash during PMDD episodes - from GABA and serotonin pathways to cortisol regulation and neuroinflammation.
Below you'll find the key studies we used to design Lutea's comprehensive approach to PMDD brain chemistry support.
Because when you're dealing with a condition that affects your identity, relationships, and quality of life - you deserve solutions based on real science, not marketing claims.
2007 Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene Huo L, et al Biol Psych
2020 Allopregnanolone in PMDD: evidence for dysregulated GABA-A sensitivity. Hantsoo L, Epperson CN. Neurobiol Stress.
2022 GABA(A) receptor modulating steroids and clinical implications. Bäckström T et al.. J Neuroendocrinol.
2023 Allopregnanolone-mediated GABAA-Rα4 function in amygdala and hippocampus of PMDD Sun Y, Gao M, Gao D, Chen D, Wang J. Aging
2023 Role of allopregnanolone-mediated γ-aminobutyric acid A receptor sensitivity in the pathogenesis of PMDD Gao et al Front Psych
2025 Genetic contributions to premenstrual symptoms: revisiting the role of the ESR1 gene
Vitamin B6 (as pyridoxine hydrochloride) — 1.70 mg (100% DV)
KSM-66® Ashwagandha extract (Withania somnifera) (Root)
Maca 10:1 extract (Lepidium meyenii) (Root)
Chaste Tree 20:1 extract (Vitex agnus-castus) (Berry)
Wild Yam 8:1 extract (Dioscorea oppositifolia) (Root)
Broccoli 20:1 extract (Brassica oleracea) (Sprout)
Fennel Seed Powder Extract 10:1 (Foeniculum vulgare) (Seed)
Berberine 15:1 extract (Phellodendron amurense) (Bark)
Gymnema Extract 4:1 (Gymnema sylvestre) (Leaf)
Rosemary Extract 8:1 (Rosmarinus officinalis) (Leaf)
Chamomile 10:1 extract (Matricaria chamomilla) (Flower)
Rhodiola 10:1 extract (Rhodiola rosea) (Root)
Hypromellose (vegetable capsule)
Organic rice extract
We’ve done our homework and made sure every ingredient is included in the right amount to truly make a difference. While many brands sprinkle in tiny doses just to put them on the label, we don’t play that game. Every dosage in our formula is backed by scientific research showing it can help ease PMDD symptoms.
Take back control over your life and future. Love, Feel and be yourself all Month long.
Give your body the exact 11 nutrients it needs to reset your brain’s hormone-response system.
The ingredients start buffering hormone shifts, balancing mood chemicals, and calming stress responses — so your brain stops overreacting to your cycle.
With each cycle, your mood, energy, and resilience improve as your system relearns to ride hormonal changes without crashing.
92%
Reduced the intensity of their PMDD symptoms within just one month of use.
89%
Took back control of their bodies—and finally started living a normal life again.
0%
Zero reported side effects after consistent use.
Based on feedback from 200 women with PMDD who took Lutea daily for 5 months.
We had enough of cheap PMS Elixiers or random Medications numbing us. We needed something that works!
  | Lutea | Others |
---|---|---|
Just for PMDD | ||
Natural Ingredients | ||
Targets Root Cause | ||
All Pathways Covered | ||
Backed by Real PMDD Experience | ||
Science-backed, 3rd-party tested | ||
Hormone-free, allergen-free, vegan |
From scientists and dieticians, to gynaecologists and psychologists, we work with experts who are the best at what they do.
So you can get back to being the best at what you do.
We know real healing takes time and consistency. And because every woman responds differently to Lutea, we give you 90 full days to try it—risk-free. If it’s not right for you, we’ll make it right. No stress. No questions.
Most supplements try to fix your hormones. Your hormones aren't broken - your brain just can't handle them changing.
Lutea supports your brain's calming system (GABA) so you don't spiral when hormones shift. Plus it's all the proven ingredients in one bottle instead of buying 11 separate ones.
No. Lutea doesn't change your hormone levels at all. It helps your brain handle normal hormone changes without freaking out.
All plant-based ingredients that work with your body, not against it. But check with your doctor if you're on other meds.
Full money back, no questions asked.
The ingredients are clinically dosed for mood and stress support. Most women see improvements in 4-8 weeks. If you don't, you get every penny back.
You can cancel anytime by just sending us an email. No hassle, no hoops to jump through.
Just shoot us a message and we'll take care of it right away. We're not here to make canceling difficult - if it's not working for you, that's totally fine.
Most women notice less intense mood swings within 2-3 weeks. Full benefits usually kick in around 4-8 weeks of consistent use.
Your brain needs time to build up the nutrients it's been missing.
All natural plant-based ingredients, but definitely check with your doctor first.
Most ingredients like ashwagandha and chamomile are generally safe, but your doctor knows your specific situation best.
Just get back on track the next day. Consistency works best, but missing a day here and there won't ruin your progress.
It's only 2 capsules a day - way easier than managing 11 different supplement schedules.
Many of our ingredients support overall mood and stress response, so you might see benefits there too.
But this is specifically formulated for PMDD - the brain-hormone sensitivity issue. It's not a replacement for other treatments you might need.
Third-party tested for purity and potency. Made in an FDA-registered facility.
We spent 1.5 years getting this right because we were going to put it in our own bodies. Were not cutting corners on quality.
As long as you're cycling, your brain will need support handling hormone changes.
Think of it like taking a daily multivitamin - it's ongoing support, not a quick fix that disappears when you stop.